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    Methods Mol Biol. 2007;395:293-308.

    Discovery of conserved motifs in promoters of orthologous genes in prokaryotes.

    Source

    Université Libre de Bruxelles.

    Abstract

    We present a method to predict cis-acting elements for a given gene by detecting over-represented motifs in promoters of a set of ortholo gous genes in prokaryotes (single-gene, multiple-genomes approach). The method has been used successfully to detect regulatory elements at various taxonomical levels in prokaryotes. A web interface is available at the Regulatory Sequence Analysis Tools site (http://rsat.scmbb.ulb.ac.be/rsat/).

    PMID:
    17993681
    [PubMed - indexed for MEDLINE]

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