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Genome Res. 2007 Dec;17(12):1783-6. Epub 2007 Nov 7.

A second-generation combined linkage physical map of the human genome.

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  • 1Department of Genetics, Rutgers University, Piscataway, New Jersey 08854, USA. matise@biology.rutgers.edu


We have completed a second-generation linkage map that incorporates sequence-based positional information. This new map, the Rutgers Map v.2, includes 28,121 polymorphic markers with physical positions corroborated by recombination-based data. Sex-averaged and sex-specific linkage map distances, along with confidence intervals, have been estimated for all map intervals. In addition, a regression-based smoothed map is provided that facilitates interpolation of positions of unmapped markers on this map. With nearly twice as many markers as our first-generation map, the Rutgers Map continues to be a unique and comprehensive resource for obtaining genetic map information for large sets of polymorphic markers.

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