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Infectious Disease Unit, Sheba Medical Center, Tel Hashomer, Israel.
Typhoid fever is no longer endemic to most developed countries, including Israel. When encountered, it usually occurs in travelers returning from endemic countries. Worldwide, the disease is far from being eradicated. It is still highly prevalent in some popular travel destinations such as India. With the continued increase in Israelis traveling to (and in migrant workers arriving from) endemic regions, physicians in Israel should be well acquainted with the disease. Unfortunately, with the limited efficacy of the current typhoid vaccinations and the increase in multidrug-resistant strains, cases among travelers are expected to continue to increase and become ever challenging to treat.
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