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1: Curr Opin Drug Discov Devel. 2007 Nov;10(6):768-83.Links

The synthesis of naturally occurring peptides and their analogs.

Cupido T, Tulla-Puche J, Spengler J, Albericio F.

Institute for Research in Biomedicine, Barcelona Science Park, University of Barcelona, Josep Samitier 1-5, Barcelona, Spain.

The number of peptide-based pharmaceuticals has increased enormously over recent years; some of these peptides are derived from natural sources, and many are large and complex. This review provides an overview of the current state of peptide synthesis methodology, focusing mainly on the synthesis of natural peptides and their analogs.

PMID: 17987528 [PubMed - indexed for MEDLINE]