Display Settings:


Send to:

Choose Destination
See comment in PubMed Commons below
FEMS Microbiol Lett. 2007 Dec;277(1):64-9.

Virulence of clinical and environmental isolates of Burkholderia oklahomensis and Burkholderia thailandensis in hamsters and mice.

Author information

  • Bacteriology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD, USA. david.deshazer@amedd.army.mil


Burkholderia pseudomallei is the etiologic agent of the tropical disease melioidosis and is considered to be a potential biological weapon. Two B. pseudomallei-like species, Burkholderia oklahomensis and Burkholderia thailandensis, have been described in the literature. Infections with both of these microorganisms have occurred in the United States, but little is known about the relative virulence of these isolates in animal models of infection. In this study, B. oklahomensis and B. thailandensis CDC2721121 were determined to be avirulent in hamsters and mice at all challenge doses examined. The virulence of B. thailandensis CDC3015869, on the other hand, was more similar to the virulence of isolates of B. thailandensis from Southeast Asia.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Icon for Blackwell Publishing Icon for Faculty of 1000
    Loading ...
    Write to the Help Desk