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J Zhejiang Univ Sci B. 2007 Nov;8(11):815-21.

WOMBAT: a tool for mixed model analyses in quantitative genetics by restricted maximum likelihood (REML).

Author information

  • 1Animal Genetics and Breeding Unit, University of New England, Armidale, NSW, Australia. kmeyer@didgeridoo.une.edu.au

Abstract

WOMBAT is a software package for quantitative genetic analyses of continuous traits, fitting a linear, mixed model; estimates of covariance components and the resulting genetic parameters are obtained by restricted maximum likelihood. A wide range of models, comprising numerous traits, multiple fixed and random effects, selected genetic covariance structures, random regression models and reduced rank estimation are accommodated. WOMBAT employs up-to-date numerical and computational methods. Together with the use of efficient compilers, this generates fast executable programs, suitable for large scale analyses. Use of WOMBAT is illustrated for a bivariate analysis. The package consists of the executable program, available for LINUX and WINDOWS environments, manual and a set of worked example, and can be downloaded free of charge from (http://agbu. une.edu.au/~kmeyer/wombat.html).

PMID:
17973343
[PubMed - indexed for MEDLINE]
PMCID:
PMC2064953
Free PMC Article
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