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    Ugeskr Laeger. 2007 Oct 22;169(43):3655-60.

    [Vitamin D insufficiency--possible etiologic factor of autoimmune diseases].

    [Article in Danish]

    Source

    Arhus Universitetshospital, Arhus Sygehus, Medicinsk Hepato-gastroenterologisk Afdeling V. spgjo@as.aaa.dk

    Abstract

    The primary source of vitamin D in humans is sun exposure to the skin. The incidence of certain autoimmune diseases correlates positively with latitude. As vitamin D production increases with sun exposure, vitamin D insufficiency is hypothesised to influence the development of autoimmune diseases. In experimental animal and cellular studies in vitro 1.25-(OH)2-vitamin D reduces inflammation. This article discusses the role of vitamin D in inflammatory bowel disease, type 1 diabetes mellitus, multiple sclerosis, and rheumatoid arthritis.

    PMID:
    17967265
    [PubMed - indexed for MEDLINE]

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