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    Mol Cell. 2007 Oct 26;28(2):184-6.

    Achieving broad substrate specificity in damage recognition by binding accessible nondamaged DNA.

    Schärer OD.

    Department of Pharmacological Sciences, Stony Brook University, Stony Brook, NY 11974-3400, USA. orlando@pharm.stonybrook.edu

    The structure of the Rad4/Rad23 protein, shown in a recent issue of Nature (Min and Pavletich, 2007), reveals how structurally diverse lesions are recognized in eukaryotic nucleotide excision repair: by probing for accessible nondamaged DNA opposite the lesion.

    PMID: 17964258 [PubMed - indexed for MEDLINE]

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