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    Psychopharmacology (Berl). 1991;105(2):191-6.

    Prospective study of factors influencing the development of craving associated with smoking cessation.

    Killen JD, Fortmann SP, Newman B, Varady A.

    Source

    Center for Research in Disease Prevention, Stanford University School of Medicine, Palo Alto, CA 94304.

    Abstract

    There have been few prospective studies of craving following smoking cessation. This paper presents findings from a prospective examination of factors associated with craving over an 8-week treatment period. Two findings merit attention: (1) dependence, as measured by the Dependence Index (DI), was associated with craving at 48 h, 4 and 8 weeks post-cessation. The magnitude of the association between the DI and short-term craving was, at the least, comparable to that previously reported among several biochemical measures of smoke intake; (2) a measure of craving obtained 48 h after smoking cessation was associated with treatment outcome. Forty-three per cent of participants with low initial craving scores were abstinent at a 2-month follow-up compared to only 26% of those with high craving scores. The DI was also associated with participants' status at follow-up. This result is interesting because evidence that craving or other abstinence effects are prospectively associated with outcome has been lacking.

    PMID:
    1796127
    [PubMed - indexed for MEDLINE]

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