My NCBISign In

Display Settings:

Format

Send to:

Choose Destination
    J Neurosci Res. 1991 Sep;30(1):105-15.

    Identification of a tektin-like protein associated with neurofilaments in the developing chick nervous system.

    Edson KJ, Linck RW, Letourneau PC.

    Source

    Department of Cell Biology and Neuroanatomy, University of Minnesota, Minneapolis, 55455.

    Abstract

    A 160-kD polypeptide, which is recognized by an affinity-purified polyclonal antibody to the 55-kD tektin-A polypeptide from sea urchin sperm flagellar microtubules, is associated with neurofilaments in embryonic chick nerve cells. Antibodies to tektin-A and monoclonal antibodies to the neurofilament triplet proteins colocalize to filaments in cultured nerve cells and to filaments in extracts of chick spinal cord, using indirect immunofluorescence microscopy and immunogold electron microscopy. The antigen reacting with anti-tektin-A in chick brain and spinal cord extracts has been identified as a 160-kD polypeptide by SDS-PAGE and has been shown to be distinct from the known neurofilament-triplet proteins by two-dimensional immunoblot analysis. These data suggest that a unique protein with limited sequence homology to tektin-A is a component of the neuronal cytoskeleton and is incorporated into or associated with neurofilaments.

    PMID:
    1795395
    [PubMed - indexed for MEDLINE]

    Publication Types, MeSH Terms, Substances, Grant Support

    Publication Types

    MeSH Terms

    Substances

    Grant Support

    LinkOut - more resources

    Other Literature Sources

    Research Materials

      Supplemental Content

      Save items

      loading

      Related citations in PubMed

      See reviews... See all...

      Related information

      • Related Citations
        Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
      • Substance (MeSH Keyword)
        PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.

      Recent activity

      Clear Turn Off Turn On

      Your browsing activity is empty.

      Activity recording is turned off.

      Turn recording back on

      See more...
      You are here: NCBI > Literature > PubMed
      Write to the Help Desk