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J Plast Reconstr Aesthet Surg. 2007;60(11):1260-2. Epub 2006 May 11.

Involuting solitary cutaneous infantile myofibroma and thrombocytopaenia: a previously unreported clinical association.

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  • 1St Andrews Centre for Plastic Surgery, Court Road, Broomfield, Chelmsford, Essex CM1 7ET, UK.


Solitary and multicentric myofibromas are rare fibrous tumours with marked predilection for infants and young children. Presentation is mainly before the age of 2 and lesions are often congenital. Behaviour is usually benign, but mortality has been described in lesions with visceral involvement. We report a unique case of congenital solitary cutaneous infantile myofibroma in a neonate associated with self-limiting thrombocytopaenia. It is important to distinguish accurately these lesions from benign vascular tumours like haemangiomas, locally aggressive vascular tumours like Kaposiform haemangioendotheliomas, which are often associated with Kasabach-Merritt phenomenon and also with malignant soft tissue tumours of infancy.

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