Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Cell Tissue Res. 2008 Jan;331(1):359-72. Epub 2007 Oct 16.

Stem cells and tooth tissue engineering.

Author information

  • 1Department of Craniofacial Development, Dental Institute, Guy's Hospital, Kings College London, London Bridge, London, SE1 9RT, UK.

Abstract

The notion that teeth contain stem cells is based on the well-known repairing ability of dentin after injury. Dental stem cells have been isolated according to their anatomical locations, colony-forming ability, expression of stem cell markers, and regeneration of pulp/dentin structures in vivo. These dental-derived stem cells are currently under increasing investigation as sources for tooth regeneration and repair. Further attempts with bone marrow mesenchymal stem cells and embryonic stem cells have demonstrated the possibility of creating teeth from non-dental stem cells by imitating embryonic development mechanisms. Although, as in tissue engineering of other organs, many challenges remain, stem-cell-based tissue engineering of teeth could be a choice for the replacement of missing teeth in the future.

PMID:
17938970
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Icon for Springer
    Loading ...
    Write to the Help Desk