Recombinant human zona pellucida protein C produce...[Fertil Steril. 2008]

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1: Fertil Steril. 2008 Sep;90(3):879-82. Epub 2007 Oct 23. Links

Recombinant human zona pellucida protein C produced in Chinese hamster ovary cells binds to human spermatozoa and inhibits sperm-zona pellucida interaction.

Marín-Briggiler CI, Gonzalez-Echeverría MF, Harris JD, Vazquez-Levin MH.

Instituto de Biología y Medicina Experimental, National Research Council of Argentina (CONICET), Buenos Aires, Argentina.

Recombinant human zona pellucida protein C expressed in Chinese hamster ovary cells associates to the acrosomal region of human spermatozoa and inhibits sperm-zona pellucida interaction in the hemizona assay. Recombinant human zona pellucida protein C may be a useful tool toward the development of diagnostic methods for male factor infertility and the elucidation of the molecular basis of fertilization.

PMID: 17936279 [PubMed - indexed for MEDLINE]

Recombinant mouse sperm ZP3-binding protein (ZP3R/sp56) forms a high order oligomer that binds eggs and inhibits mouse fertilization in vitro.
J Biol Chem. 2008 May 2; 283(18):12438-45. Epub 2008 Mar 3.

[J Biol Chem. 2008]
Recombinant human zona pellucida protein ZP3 produced by chinese hamster ovary cells induces the human sperm acrosome reaction and promotes sperm-egg fusion.
Biol Reprod. 1994 Oct; 51(4):607-17.

[Biol Reprod. 1994]
Characterization of the biologic activities of a recombinant human zona pellucida protein 3 expressed in human ovarian teratocarcinoma (PA-1) cells.
Am J Obstet Gynecol. 2001 Apr; 184(5):835-43; discussion 843-4.

[Am J Obstet Gynecol. 2001]
ReviewMolecular mechanisms of the interaction between sperm and the zona pellucida in mammals: studies on the pig.
Int J Androl. 1995 Dec; 18 Suppl 2:20-6.

[Int J Androl. 1995]
ReviewBiochemical and functional characterization of the human zona pellucida.
Reprod Biomed Online. 2003 Dec; 7(6):641-8.

[Reprod Biomed Online. 2003]
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Recombinant human zona pellucida protein C produced in Chinese hamster ovary cells binds to human spermatozoa and inhibits sperm-zona pellucida interaction.

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