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    Dig Dis Sci. 2008 Apr;53(4):1100-6. Epub 2007 Oct 13.

    Assessment of the PHQ-9 as a screening tool for depression in patients with chronic hepatitis C.

    Dbouk N, Arguedas MR, Sheikh A.

    Source

    Department of Internal Medicine, The University of Alabama at Birmingham, 1530 3rd Avenue South BDB 327, Birmingham, AL 35294, USA. ndbouk@gmail.com

    Abstract

    BACKGROUND AND OBJECTIVES:

    We examined the test characteristics of the PHQ-9, a new screening tool that has been validated in the general population but not amongst patients with hepatitis C virus (HCV).

    METHODS:

    The PHQ-9, CES-D and BDI-II questionnaires were administered to 129 consecutive patients with chronic HCV attending a specialty clinic between August 2005 and April 2006.

    RESULTS:

    Approximately 52% of participants reported symptoms suggesting depression. Prevalence of depression was 62% using the BDI-II, 75% per the PHQ-9 and 72% per the CES-D. We observed a strong correlation between the BDI-II, CES-D and PHQ-9 in patients on and off interferon. Scores on the three questionnaires were only moderately associated with symptoms reported by the patients. There was moderate agreement between the CES-D and BDI-II and slight agreement between both these questionnaires and the PHQ-9. Scores on the PHQ-9 correlated strongly with scores on the CES-D and BDI-II and moderately with patients' symptoms.

    PMID:
    17934817
    [PubMed - indexed for MEDLINE]

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