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Phys Rev E Stat Nonlin Soft Matter Phys. 2007 Aug;76(2 Pt 1):020901. Epub 2007 Aug 23.

Quantized cycling time in artificial gene networks induced by noise and intercell communication.

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  • 1Institut für Physik, Potsdam Universität, Am Neuen Palais 10,D-14469 Potsdam, Germany.


We propose a mechanism for the quantized cycling time based on the interplay of cell-to-cell communication and stochasticity, by investigating a model of coupled genetic oscillators with known topology. In addition, we discuss how inhomogeneity can be used to enhance such quantizing effects, while the degree of variability obtained can be controlled using the noise intensity or adequate system parameters.

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