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    Neonatal Netw. 2007 Sep-Oct;26(5):335-51.

    Spontaneous intestinal perforation.

    Donahue L.

    John's Mercy Medical Center in St Louis, USA. misslaurad@gmail.com

    So much is unknown about SIP-its etiology, pathophysiology, best treatment modality, and outcome. Yet the incidence of SIP is increasing as more VLBW infants are surviving and since SIP has been identified as a separate disease from NEC. Because many cases present with an insidious onset, it is imperative that practitioners review all x-rays with SIP in mind. Although SIP is a relatively rare occurrence in the NICU, its potential to increase morbidity and mortality in premature infants warrants further research to improve outcomes.

    PMID: 17926662 [PubMed - indexed for MEDLINE]

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