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Geriatrics. 2007 Oct;62(10):13-6.

Restless legs syndrome: nonpharmacologic and pharmacologic treatments.

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  • 1Division of Sleep Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass, USA.


Treatment of restless legs syndrome (RLS) has as its goals alleviation of the primary symptoms of the disorder and establishment of normal sleep. Dopamine agonists are considered first-line treatment when daily treatment for primary RLS is indicated. Gabapentin and opioids may be of value for refractory cases. Initial treatment of secondary RLS should address the underlying cause.

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