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Int J Legal Med. 2008 May;122(3):251-5. Epub 2007 Oct 2.

Analysis of Y-chromosomal SNP haplogroups and STR haplotypes in an Algerian population sample.

Author information

  • 1Department of Anatomy, Pharmacology and Legal Medicine, University of Turin, Turin, Italy. carlo.robino@unito.it

Abstract

The distribution of Y-chromosomal single nucleotide polymorphism (SNP) haplogroups and short tandem repeat (STR) haplotypes was determined in a sample of 102 unrelated men of Arab origin from northwestern Algeria (Oran area). A total of nine different haplogroups were identified by a panel of 22 binary markers. The most common haplogroups observed in the Algerian population were E3b2 (45.1%) and J1 (22.5%). Y-STR typing by a 17-loci multiplex system allowed 93 haplotypes to be defined (88 were unique). Striking differences in the allele distribution and gene diversity of Y-STR markers between haplogroups could be found. In particular, intermediate alleles at locus DYS458 specifically characterized the haplotypes of individuals carrying haplogroup J1. All the intermediate alleles shared a common repeat sequence structure, supporting the hypothesis that the variant originated from a single mutational event.

PMID:
17909833
[PubMed - indexed for MEDLINE]
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