Anal Bioanal Chem. 2008 Jan;390(1):3-16. Epub 2007 Oct 2.

Elemental mass spectrometry for quantitative proteomics.

Sanz-Medel A, Montes-Bayón M, del Rosario Fernández de la Campa M, Encinar JR, Bettmer J.

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Department of Physical and Analytical Chemistry, Faculty of Chemistry, University of Oviedo, C/Julián Clavería 8, 33006, Oviedo, Spain. asm@uniovi.es

Abstract

In the last decade mass-spectrometry-based proteomics has become an indispensable analytical tool for molecular biology, cellular biology and, lately, for the emerging systems biology. This review summarises the evolution and great potential of analytical methods based on elemental mass-spectrometric detection for quantitative proteomic analysis.

PMID:: 17909759; [PubMed - indexed for MEDLINE]

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