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Am J Obstet Gynecol. 2007 Dec;197(6):594.e1-6. Epub 2007 Oct 1.

The association of tea consumption with ovarian cancer risk: A metaanalysis.

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  • 1Key Laboratory of Reproductive Medicine, Department of Pharmacology, Nanjing Medical University, Nanjing, Jiangsu Province, China.

Abstract

OBJECTIVE:

This metaanalysis was undertaken to evaluate the relationship between tea intake and ovarian cancer risk.

STUDY DESIGN:

A systematic literature search up to September 2006 was performed in Medline, Embase, CANCERLIT, and the Cochrane Database. The summary relative risk was calculated. A sensitivity analysis was conducted to test the influence of each single study. Heterogeneity and publication bias were also evaluated.

RESULTS:

Two cohort and 7 case-control studies were included. The combined relative risk did not show that tea consumption was associated with a reduced ovarian cancer risk (relative risk, 0.84; 95% confidence interval, 0.66-1.07). When the analyses were stratified into subgroups, there was no evidence that study design substantially influenced the estimate of effects. The sensitivity analysis which means removing one study at a time confirmed the stability of our results.

CONCLUSION:

Our findings did not support that tea consumption was related to the decreased risk of ovarian cancer.

PMID:
17905170
[PubMed - indexed for MEDLINE]
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