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Liver Int. 2008 Apr;28(4):574-7. Epub 2007 Sep 26.

Non-transplant surgical approach to liver-based hereditary haemorrhagic telangiectasia: a first report.

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  • 1Department of Transplant Surgery, University of L'Aquila, San Salvatore Hospital, L'Aquila, Italy.


A 55-year-old woman with hereditary haemorrhagic telangiectasia (HHT) underwent a left lateral liver bisegmentectomy (removal of segments 2 and 3) for hepatic-based arteriovenous malformations. This lesion determined a progressive fatigue and invalidating effort dyspnoea. The postoperative course was uneventful and the patient is currently doing well at 4 years after surgery. To our knowledge, this is the first case of hepatic-based HHT treated with liver resection. This anecdotal report should promote the evaluation of this approach in order to define its role in the treatment of liver involvement in this rare disease.

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