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Institute for Research in Biomedicine, Barcelona Science Park, Josep Samitier 1, 08028-Barcelona, Spain. aymanel_faham@hotmail.com
A novel proton acceptor coupling reagent shows superiority to those described previously. The oxygen in the carbocation moiety confers more solubility to the reagent. Furthermore, it enhances coupling yields and decreases racemization, allowing the use of 1 equiv of base.
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