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Altern Ther Health Med. 2007 Sep-Oct;13(5):54-9.

Potential of rosemary oil to be used in drug-resistant infections.

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  • 1Genetic Resources and Biotechnology Division, Central Institute of Medicinal and Aromatic Plants (Council of Scientific and Industrial Research), Lucknow, India.

Abstract

OBJECTIVE:

To evaluate the antimicrobial activity potential of the essential oil of rosemary specifically for its efficacy against the drug-resistant mutants of Mycobacterium smegmatis, Escherichia coli, and Candida albicans.

METHOD:

Antibacterial, antifungal, and drug resistance-modifying activity was evaluated both qualitatively and quantitatively following disc diffusion and broth dilution assay procedures.

RESULTS:

The rosemary essential oil was found to be more active against the gram-positive pathogenic bacteria except E. faecalis and drug-resistant mutants of E. coli, compared to gram-negative bacteria. Similarly, it was found to be more active toward nonfilamentous, filamentous, dermatophytic pathogenic fungi and drug-resistant mutants of Candida albicans.

CONCLUSION:

Our findings suggest that characterization and isolation of the active compound(s) from the rosemary oil may be useful in counteracting gram-positive bacterial, fungal, and drug-resistant infections.

PMID:
17900043
[PubMed - indexed for MEDLINE]
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