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Balsalazide-induced myocarditis.
A 38 year-old man with ulcerative colitis recently treated with balsalazide was admitted with chest pain. Investigations demonstrated myocardial necrosis, ECG changes, echocardiographic wall motion abnormalities but normal epicardial coronary arteries and no LV scar on cardiac MRI. Myocarditis was diagnosed and balsalazide therapy was withdrawn, resulting in a full recovery and resolution of abnormalities.
PMID: 17889383 [PubMed - indexed for MEDLINE]
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Patient Drug Information
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Mesalamine (Asacol® , Canasa® , Pentasa® , ...)
Mesalamine is used to treat ulcerative colitis (a condition in which part or all of the lining of the colon [large intestine] is swollen or worn away). Mesalamine delayed-release tablets and controlled-release capsules m...
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Balsalazide (Colazal® )
Balsalazide is used to treat ulcerative colitis, a condition in which the bowel is inflamed. Balsalazide is an anti-inflammatory drug. It is converted in the body to mesalamine and works by reducing bowel inflammation, d...