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1: J Med Case Reports. 2007 Sep 22;1:101.Click here to read Click here to read Links

Pulmonary cystic disease in HIV positive individuals in the Democratic Republic of Congo: three case reports.

Callens SF, Kitetele F, Lelo P, Shabani N, Lusiama J, Wemakoy O, Colebunders R, Behets F, Van Rie A.

School of Public Health, University of North Carolina at Chapel Hill, USA. callens@email.unc.edu.

ABSTRACT: Pulmonary emphysema and bronchiectasis in HIV seropositive patients has been described in the presence of injection drug use, malnutrition, repeated opportunistic infections, such as Pneumocytis jirovici pneumonia and Mycobacterium tuberculosis infection, and has been linked to the presence of HIV virus in lung tissue. Given the high burden of pulmonary infections and malnutrition among people living with HIV in resource poor settings, these individuals may be at increased risk of developing pulmonary emphysema, potentially reducing the long term benefit of antiretroviral therapy (ART) if initiated late in the course of HIV infection.In this report, we describe three HIV-infected individuals (one woman and two children) presenting with extensive pulmonary cystic disease.

PMID: 17888170 [PubMed - in process]

PMCID: PMC2082036