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    Sci China C Life Sci. 2007 Oct;50(5):619-23.

    The molecular mechanism of embryonic stem cell pluripotency and self-renewal.

    Liu Y, Ji L, Ten Y, Wang Y, Pei X.

    Source

    Laboratory of Stem Cell Biology, Beijing Institution of Transfusion Medicine, Beijing 100850, China.

    Abstract

    The self-renewal and pluripotency of embryonic stem cells (ESCs) is regulated by a network, which consists of a series of cell factors in microenviroments, a chain of transcription factors and certain signal conduction pathways. This article reviews recent progress in this field to elucidate the mechanism involved.

    PMID:
    17879059
    [PubMed - indexed for MEDLINE]

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