J Rheumatol. 1991 Nov;18(11):1685-8.

Sjögren's syndrome in patients with the CREST variant of progressive systemic scleroderma.

Drosos AA, Pennec YL, Elisaf M, Lamour A, Acritidis NC, Jouquan JR, Moutsopoulos HM, Youinou P.

Source

Department of Internal Medicine, School of Medicine, Universita of Ioannina, Greece.

Abstract

Twenty-three patients with the CREST (calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly, telangiectasia) variant of progressive systemic sclerosis, were clinically, histopathologically and serologically examined for the presence of Sjögren's syndrome (SS). Fourteen were found to be positive. No significant difference could be demonstrated between them and the remaining 9. Characteristics of patients with CREST were compared with those of 29 randomly chosen patients with primary SS. Parotid gland enlargement was more frequently present (p less than 0.01) in the latter than in the former. Virtually no patients with CREST with SS had antibodies to Ro(SSA)/La(SSB).

Comment in

J Rheumatol. 1993 Jan;20(1):203-4.

PMID:: 1787489; [PubMed - indexed for MEDLINE]

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Research Support, Non-U.S. Gov't

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Autoantibodies

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Cited by 3 PubMed Central articles

Prevalence and clinical relevance of 52-kDa and 60-kDa Ro/SS-A autoantibodies in Japanese patients with systemic sclerosis. [Ann Rheum Dis. 1997]
Prevalence and clinical relevance of 52-kDa and 60-kDa Ro/SS-A autoantibodies in Japanese patients with systemic sclerosis.
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The European Community Study Group on diagnostic criteria for Sjögren's syndrome. Sensitivity and specificity of tests for ocular and oral involvement in Sjögren's syndrome. [Ann Rheum Dis. 1994]
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