A case of Philadelphia-chromosome positive chronic idiopathic myelofibrosis

Feng Chen; Chunqing Zhang; Wen Wang; Lizhen Li; Shuxin Yan; Jianzhi Sun; Maohong Zhang; Chunyan Ji; Ming Hou

doi:10.1016/j.leukres.2007.08.001

A case of Philadelphia-chromosome positive chronic idiopathic myelofibrosis

Leuk Res. 2008 Apr;32(4):665-7. doi: 10.1016/j.leukres.2007.08.001. Epub 2007 Sep 12.

Authors

Feng Chen¹, Chunqing Zhang, Wen Wang, Lizhen Li, Shuxin Yan, Jianzhi Sun, Maohong Zhang, Chunyan Ji, Ming Hou

Affiliation

¹ Department of Hematology, Qilu Hospital,Shandong University, Jinan, PR China.

PMID: 17854891
DOI: 10.1016/j.leukres.2007.08.001

Abstract

Philadelphia-chromosome positive thrombocythemia without features of chronic myeloid leukemia in peripheral blood has been described before. However, there are few reports on Philadelphia-chromosome positive chronic idiopathic myelofibrosis. We present a case of Philadelphia positive chronic idiopathic myelofibrosis that had no obvious response to imatinib.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Benzamides
Chronic Disease
Humans
Imatinib Mesylate
Male
Middle Aged
Myeloproliferative Disorders / drug therapy
Myeloproliferative Disorders / pathology*
Philadelphia Chromosome*
Piperazines / therapeutic use
Primary Myelofibrosis / drug therapy
Primary Myelofibrosis / pathology*
Pyrimidines / therapeutic use

Substances

Benzamides
Piperazines
Pyrimidines
Imatinib Mesylate