Cancer Genet Cytogenet. 2007 Sep;177(2):131-4.

Cellular angiofibroma is genetically similar to spindle cell lipoma: a case report.

Hameed M, Clarke K, Amer HZ, Mahmet K, Aisner S.

Source

Department of Pathology, University of Medicine and Dentistry of New Jersey--New Jersey Medical School, 150 Bergen Street, UHE-141, Newark, NJ 07103, USA. hameedmr@umdnj.edu

Abstract

Cellular angiofibroma is a benign mesenchymal neoplasm of female and male genital tract composed of prominent vasculature and stromal spindle cells, often with admixture of adipose tissue. The tumor has histomorphologic similarities to angiomyofibroblastoma and spindle cell lipoma. Herein we describe a tumor arising in the perineal region of a 60-year-old man with morphological and immunohistochemical features of cellular angiofibroma and showing cytogenetic characteristics similar to spindle cell lipoma. To our knowledge, this is the first report of cytogenetic changes in cellular angiofibroma. The genetic overlap of these entities supports their origin from the same mesenchymal stem cell.

PMID:: 17854668; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms

Publication Types

Case Reports

MeSH Terms

LinkOut - more resources

Full Text Sources

Other Literature Sources

Medical

Supplemental Content

Related citations

Cellular angiofibroma: analysis of 25 cases emphasizing its relationship to spindle cell lipoma and mammary-type myofibroblastoma. [Mod Pathol. 2011]
Cellular angiofibroma: analysis of 25 cases emphasizing its relationship to spindle cell lipoma and mammary-type myofibroblastoma.
Flucke U, van Krieken JH, Mentzel T. Mod Pathol. 2011 Jan; 24(1):82-9. Epub 2010 Sep 17.
Angiomyofibroblastomalike tumor of the male genital tract: analysis of 11 cases with comparison to female angiomyofibroblastoma and spindle cell lipoma. [Am J Surg Pathol. 1998]
Angiomyofibroblastomalike tumor of the male genital tract: analysis of 11 cases with comparison to female angiomyofibroblastoma and spindle cell lipoma.
Laskin WB, Fetsch JF, Mostofi FK. Am J Surg Pathol. 1998 Jan; 22(1):6-16.
Cellular angiofibroma: a benign neoplasm distinct from angiomyofibroblastoma and spindle cell lipoma. [Am J Surg Pathol. 1997]
Cellular angiofibroma: a benign neoplasm distinct from angiomyofibroblastoma and spindle cell lipoma.
Nucci MR, Granter SR, Fletcher CD. Am J Surg Pathol. 1997 Jun; 21(6):636-44.
Review [Cellular angiofibroma. A rare vulvar tumor. Report of a case]. [Ann Pathol. 2001]
Review [Cellular angiofibroma. A rare vulvar tumor. Report of a case].
Colombat M, Liard-Meillon ME, De Saint-Maur P, Sevestre H, Gontier MF. Ann Pathol. 2001 Apr; 21(2):145-8.
Review Intramuscular spindle cell lipoma: Case report and review of the literature. [Pathol Int. 2001]
Review Intramuscular spindle cell lipoma: Case report and review of the literature.
Horiuchi K, Yabe H, Nishimoto K, Nakamura N, Toyama Y. Pathol Int. 2001 Apr; 51(4):301-4.

See reviews... See all...

Cited by 2 PubMed Central articles

Left supraclavicular spindle cell lipoma. [Int J Otolaryngol. 2010]
Left supraclavicular spindle cell lipoma.
Olaleye O, Fu B, Moorthy R, Lawson C, Black M, Mitchell D. Int J Otolaryngol. 2010; 2010:942152. Epub 2010 May 25.
Cellular angiofibroma of oral mucosa: report of two cases. [Head Neck Pathol. 2009]
Cellular angiofibroma of oral mucosa: report of two cases.
Eversole LR. Head Neck Pathol. 2009 Jun; 3(2):136-9. Epub 2009 May 31.

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Cancer Chromosomes
Cancer chromosome records that cite the current articles.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Cellular angiofibroma is genetically similar to spindle cell lipoma: a case repo...
Cellular angiofibroma is genetically similar to spindle cell lipoma: a case report.
Cancer Genet Cytogenet. 2007 Sep ;177(2):131-4.

PubMed
Frequent detection of androgen receptors in spindle cell lipomas: an explanation...
Frequent detection of androgen receptors in spindle cell lipomas: an explanation for this lesion's male predominance?
Arch Pathol Lab Med. 2008 Jan ;132(1):81-3.

PubMed
Fine-needle aspiration diagnosis of spindle-cell lipoma: a case report and revie...
Fine-needle aspiration diagnosis of spindle-cell lipoma: a case report and review of the literature.
Diagn Cytopathol. 2000 Nov ;23(5):362-5.

PubMed
Spindle-cell lipoma. A clinical, light- and electron-microscopical study.
Spindle-cell lipoma. A clinical, light- and electron-microscopical study.
Am J Surg Pathol. 1981 Jul ;5(5):435-41.

PubMed
Spindle cell lipoma.
Spindle cell lipoma.
Cancer. 1975 Nov ;36(5):1852-9.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Display Settings:

Send to: