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1: Crit Care. 2007;11(4):161.Click here to read Click here to read Links
Comment on:
Crit Care. 2007;11(4):R85.

Factor VII and the brain: time to get this research done!

Dutton RP.

Traumatic brain injury is the leading killer after trauma, in part because of coagulopathy. Factor VIIa may be a useful therapy in this setting, depending on the relative risk for thromboembolic complications. Kluger and coworkers recently conducted a retrospective review of patients with traumatic brain injury from a previous factor VIIa and trauma trial. It documents an encouragingly low rate of complications, and should provide a strong incentive to conduct a prospective study of factor VIIa in patients with severe traumatic brain injury.

PMID: 17850678 [PubMed - indexed for MEDLINE]

PMCID: PMC2206492