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Pain. 1991 Dec;47(3):337-9.

Hyperalgesia and myoclonus with intrathecal infusion of high-dose morphine.

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  • 1Pain Therapy and Palliative Care Division, National Cancer Institute of Milan, Italy.

Abstract

We report the case of a patient who developed myoclonus and hyperalgesia following administration of high-dose subarachnoid morphine. This complication occurred with 40-80 mg/day continuous infusion. The pathophysiology of these side effects is discussed.

PMID:
1784504
[PubMed - indexed for MEDLINE]
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