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J Clin Immunol. 2008 Jan;28(1):14-20. Epub 2007 Sep 9.

Biology of dendritic cells in aging.

Author information

  • 1Division of Basic and Clinical Immunology, University of California, Irvine, CA 92697, USA. aagrawal@uci.edu

Abstract

Dendritic cells are central to the generation of both immunity and tolerance. This review focuses on the alterations in the functions of dendritic cells in aged and its consequences on both tolerance and immunity. We have discussed certain mechanisms responsible for the defective dendritic cell function associated with aging.

PMID:
17828583
[PubMed - indexed for MEDLINE]
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