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Am J Obstet Gynecol. 2007 Sep;197(3):253.e1-3.

Are women who have had a preterm twin delivery at greater risk of preterm birth in a subsequent singleton pregnancy?

Author information

  • 1Department of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA. f-facco@md.northwestern.edu

Abstract

OBJECTIVE:

The purpose of this study was to determine whether preterm birth of twins is associated with an increased risk of preterm birth in a subsequent singleton pregnancy.

STUDY DESIGN:

All patients who delivered a twin gestation and a subsequent singleton pregnancy at Northwestern Memorial Hospital during a 10-year period were identified. We used a cohort study design, comparing the outcomes of the singleton pregnancies in women with preterm twin deliveries to those pregnancies with term twin deliveries.

RESULTS:

One hundred sixty-seven women delivered twins followed by a singleton pregnancy. Women whose twin delivery was preterm (n = 99) were more likely than those who had delivered a term twin pregnancy (n = 68) to deliver a subsequent preterm singleton pregnancy (13.1% vs 2.9%; odds ratio, 5.0; 95% CI, 1.1, 22.9).

CONCLUSION:

Preterm birth of twins is associated with an increased risk of preterm delivery in a subsequent singleton pregnancy.

PMID:
17826408
[PubMed - indexed for MEDLINE]
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