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Lancet. 2007 Sep 22;370(9592):1089-100.

The cardiovascular toll of stress.

Author information

  • 1Department of Medicine, Johns Hopkins Hospital, Baltimore, MD 21287, USA. brotman@jhmi.edu

Erratum in

  • Lancet. 2007 Dec 1;370(9602):1828.

Abstract

Psychological stress elicits measurable changes in sympathetic-parasympathetic balance and the tone of the hypothalamic-pituitary-adrenal axis, which might negatively affect the cardiovascular system both acutely-by precipitating myocardial infarction, left-ventricular dysfunction, or dysrhythmia; and chronically-by accelerating the atherosclerotic process. We provide an overview of the association between stress and cardiovascular morbidity, discuss the mechanisms for this association, and address possible therapeutic implications.

PMID:
17822755
[PubMed - indexed for MEDLINE]
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