Science. 1977 Apr 15;196(4287):322-3.

Alzheimer's disease, trisomy 21, and myeloproliferative disorders: associations suggesting a genetic diathesis.

Abstract

Relatives of probands with Alzheimer's disease had excessive incidences of trisomy 21 and myeloproliferative disorders. Microtubules are structures that are likely to be affected by a genetic defect causing a predisposition to Alzheimer's disease, trisomy 21 and, possibly, to myeloproliferative disorders.

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Alzheimer's disease, trisomy 21, and myeloproliferative disorders: associations ...
Alzheimer's disease, trisomy 21, and myeloproliferative disorders: associations suggesting a genetic diathesis.
Science. 1977 Apr 15 ;196(4287):322-3.

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Alzheimer's disease, trisomy 21, and myeloproliferative disorders: associations suggesting a genetic diathesis.

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