[Traumatic submacular hemorrhage treated with rt-PA and SF6]

Arch Soc Esp Oftalmol. 2007 Aug;82(8):517-20. doi: 10.4321/s0365-66912007000800013.
[Article in Spanish]

Abstract

Case report: This patient was afflicted by a traumatic submacular hemorrhage. A posterior vitrectomy was performed and intravitreal rt-PA and SF6 were administered. Four weeks later, the visual acuity had increased from 0.1 to 0.8. No complications due to the treatment with rt-PA were reported.

Discussion: It is known that waiting for the spontaneous blood removal in such cases results in a poor visual acuity recovery due to a toxic effect of the blood products. Both rt-PA and the SF6 are useful for the treatment of submacular hemorrhages secondary to age-related macular degeneration, and this case report has shown they are also useful to lyse traumatic blood clots, thus contributing to a better recovery of visual acuity.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Adult
  • Eye Injuries / complications*
  • Humans
  • Male
  • Retinal Hemorrhage / drug therapy*
  • Retinal Hemorrhage / etiology*
  • Sulfur Hexafluoride / administration & dosage
  • Sulfur Hexafluoride / therapeutic use*
  • Time Factors
  • Tissue Plasminogen Activator / administration & dosage
  • Tissue Plasminogen Activator / therapeutic use*
  • Treatment Outcome

Substances

  • Tissue Plasminogen Activator
  • Sulfur Hexafluoride