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Int J Impot Res. 2008 Mar-Apr;20(2):173-80. Epub 2007 Aug 16.

Improvement of erectile function with Prelox: a randomized, double-blind, placebo-controlled, crossover trial.

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  • 1Department of Obstetrics and Gynecology, Medical University Sofia, Faculty of Medicine, Sofia, Bulgaria.

Abstract

In a randomly allocated, double-blind, placebo-controlled, crossover design, 50 patients with mild to moderate erectile dysfunction (ED) were treated for 1 month with placebo or a combination of L-arginine aspartate and Pycnogenol (Prelox). Patients reported sexual function from diaries. Testosterone levels and endothelial NO synthase (e-NOS) were monitored along with routine clinical chemistry. Intake of Pycnogenol for 1 month restored erectile function to normal. Intercourse frequency doubled. e-NOS in spermatozoa and testosterone levels in blood increased significantly. Cholesterol levels and blood pressure were lowered. No unwanted effects were reported. Prelox is a promising alternative to treat mild to moderate ED.

PMID:
17703218
[PubMed - indexed for MEDLINE]
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