Refinement of the localization of human butyrylcho...[Genomics. 1991]

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1: Genomics. 1991 Oct;11(2):455-8. Links

Refinement of the localization of human butyrylcholinesterase to chromosome 3q26.1-q26.2 using a PCR-derived probe.

Gaughan G, Park H, Priddle J, Craig I, Craig S.

Biochemistry Department, University of Oxford, United Kingdom.

The gene for butyrylcholinesterase (EC 3.1.1.8) has been previously localized to three sites in the human genome, at 3q21, 3q26, and 16q21. In situ hybridization using a PCR-derived probe including the active site region gives a single hybridization signal and refines the localization to 3q26.1-q26.2.

PMID: 1769658 [PubMed - indexed for MEDLINE]

The cloned butyrylcholinesterase (BCHE) gene maps to a single chromosome site, 3q26.
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Human acetylcholinesterase and butyrylcholinesterase are encoded by two distinct genes.
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Reciprocal translocation (3;5)(q26;q22) and possible BCHE gene involvement in an unusual myelogenous disorder with both myeloproliferative and dysplastic features.
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Expression of alternatively terminated unusual human butyrylcholinesterase messenger RNA transcripts, mapping to chromosome 3q26-ter, in nervous system tumors.
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[Cancer Res. 1990]
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Cited by 3 PubMed Central articles

Mapping a gene for adult-onset primary open-angle glaucoma to chromosome 3q.
Wirtz MK, Samples JR, Kramer PL, Rust K, Topinka JR, Yount J, Koler RD, Acott TS. Am J Hum Genet. 1997 Feb; 60(2):296-304.

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The human gene encoding acetylcholinesterase is located on the long arm of chromosome 7.
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[Am J Hum Genet. 1992]
Identification of two different point mutations associated with the fluoride-resistant phenotype for human butyrylcholinesterase.
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[Am J Hum Genet. 1992]

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Refinement of the localization of human butyrylcholinesterase to chromosome 3q26.1-q26.2 u...Refinement of the localization of human butyrylcholinesterase to chromosome 3q26.1-q26.2 using a PCR-derived probe.

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Refinement of the localization of human butyrylcholinesterase to chromosome 3q26.1-q26.2 using a PCR-derived probe.

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Cited by 3 PubMed Central articles

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