Nat Biotechnol. 2007 Aug;25(8):894-8.

The minimum information required for reporting a molecular interaction experiment (MIMIx).

Source

European Molecular Biology Laboratory (EMBL) - European Bioinformatics Institute, Wellcome Trust Genome Campus, Cambridge, UK. orchard@ebi.ac.uk

Abstract

A wealth of molecular interaction data is available in the literature, ranging from large-scale datasets to a single interaction confirmed by several different techniques. These data are all too often reported either as free text or in tables of variable format, and are often missing key pieces of information essential for a full understanding of the experiment. Here we propose MIMIx, the minimum information required for reporting a molecular interaction experiment. Adherence to these reporting guidelines will result in publications of increased clarity and usefulness to the scientific community and will support the rapid, systematic capture of molecular interaction data in public databases, thereby improving access to valuable interaction data.

PMID:: 17687370; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms

Publication Types

Review

MeSH Terms

LinkOut - more resources

Full Text Sources

Other Literature Sources

Supplemental Content

Related citations

The HUPO PSI's molecular interaction format--a community standard for the representation of protein interaction data. [Nat Biotechnol. 2004]
The HUPO PSI's molecular interaction format--a community standard for the representation of protein interaction data.
Hermjakob H, Montecchi-Palazzi L, Bader G, Wojcik J, Salwinski L, Ceol A, Moore S, Orchard S, Sarkans U, von Mering C, et al. Nat Biotechnol. 2004 Feb; 22(2):177-83.
Review The minimum information about a proteomics experiment (MIAPE). [Nat Biotechnol. 2007]
Review The minimum information about a proteomics experiment (MIAPE).
Taylor CF, Paton NW, Lilley KS, Binz PA, Julian RK Jr, Jones AR, Zhu W, Apweiler R, Aebersold R, Deutsch EW, et al. Nat Biotechnol. 2007 Aug; 25(8):887-93.
Minimum reporting requirements for proteomics: a MIAPE primer. [Proteomics. 2006]
Minimum reporting requirements for proteomics: a MIAPE primer.
Taylor CF. Proteomics. 2006 Sep; 6 Suppl 2:39-44.
The metabolomics standards initiative. [Nat Biotechnol. 2007]
The metabolomics standards initiative.
MSI Board Members, Sansone SA, Fan T, Goodacre R, Griffin JL, Hardy NW, Kaddurah-Daouk R, Kristal BS, Lindon J, Mendes P, et al. Nat Biotechnol. 2007 Aug; 25(8):846-8.
Review Linking entries in protein interaction database to structured text: the FEBS Letters experiment. [FEBS Lett. 2008]
Review Linking entries in protein interaction database to structured text: the FEBS Letters experiment.
Ceol A, Chatr-Aryamontri A, Licata L, Cesareni G. FEBS Lett. 2008 Apr 9; 582(8):1171-7. Epub 2008 Mar 6.

See reviews... See all...

Cited by 42 PubMed Central articles

Benchmarking of the 2010 BioCreative Challenge III text-mining competition by the BioGRID and MINT interaction databases. [BMC Bioinformatics. 2011]
Benchmarking of the 2010 BioCreative Challenge III text-mining competition by the BioGRID and MINT interaction databases.
Chatr-Aryamontri A, Winter A, Perfetto L, Briganti L, Licata L, Iannuccelli M, Castagnoli L, Cesareni G, Tyers M. BMC Bioinformatics. 2011 Oct 3; 12 Suppl 8:S8. Epub 2011 Oct 3.
The IntAct molecular interaction database in 2012. [Nucleic Acids Res. 2012]
The IntAct molecular interaction database in 2012.
Kerrien S, Aranda B, Breuza L, Bridge A, Broackes-Carter F, Chen C, Duesbury M, Dumousseau M, Feuermann M, Hinz U, et al. Nucleic Acids Res. 2012 Jan; 40(Database issue):D841-6. Epub 2011 Nov 24.
MINT, the molecular interaction database: 2012 update. [Nucleic Acids Res. 2012]
MINT, the molecular interaction database: 2012 update.
Licata L, Briganti L, Peluso D, Perfetto L, Iannuccelli M, Galeota E, Sacco F, Palma A, Nardozza AP, Santonico E, et al. Nucleic Acids Res. 2012 Jan; 40(Database issue):D857-61. Epub 2011 Nov 16.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

The minimum information required for reporting a molecular interaction experimen...
The minimum information required for reporting a molecular interaction experiment (MIMIx).
Nat Biotechnol. 2007 Aug ;25(8):894-8.

PubMed
Free radicals and antioxidants in normal physiological functions and human disea...
Free radicals and antioxidants in normal physiological functions and human disease.
Int J Biochem Cell Biol. 2007 ;39(1):44-84. Epub 2006 Aug 4 .

PubMed
Pre-existing immunity against swine-origin H1N1 influenza viruses in the general...
Pre-existing immunity against swine-origin H1N1 influenza viruses in the general human population.
Proc Natl Acad Sci U S A. 2009 Dec 1 ;106(48):20365-70. Epub 2009 Nov 16 .

PubMed
Derivation of an amino acid similarity matrix for peptide: MHC binding and its a...
Derivation of an amino acid similarity matrix for peptide: MHC binding and its application as a Bayesian prior.
BMC Bioinformatics. 2009 Nov 30 ;10:394.

PubMed
Effect of baseline CD4 cell count on the efficacy and safety of peginterferon Al...
Effect of baseline CD4 cell count on the efficacy and safety of peginterferon Alfa-2a (40KD) plus ribavirin in patients with HIV/hepatitis C virus coinfection.
J Acquir Immune Defic Syndr. 2008 Jan 1 ;47(1):36-49.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Display Settings:

Send to: