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J Biomed Inform. 2007 Dec;40(6):787-802. Epub 2007 Jun 21.

Towards knowledge-based gene expression data mining.

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  • 1Dipartimento di Informatica e Sistemistica, Universit√† di Pavia, via Ferrata 1, I-27100 Pavia, Italy.


The field of gene expression data analysis has grown in the past few years from being purely data-centric to integrative, aiming at complementing microarray analysis with data and knowledge from diverse available sources. In this review, we report on the plethora of gene expression data mining techniques and focus on their evolution toward knowledge-based data analysis approaches. In particular, we discuss recent developments in gene expression-based analysis methods used in association and classification studies, phenotyping and reverse engineering of gene networks.

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