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    Genome Biol. 2007;8(8):R162.

    Microarray-based gene expression profiles in multiple tissues of the domesticated silkworm, Bombyx mori.

    Xia Q, Cheng D, Duan J, Wang G, Cheng T, Zha X, Liu C, Zhao P, Dai F, Zhang Z, He N, Zhang L, Xiang Z.

    Key Sericultural Laboratory of Agricultural Ministry, Key Laboratory for Sericultural Sciences and Genomics of the Ministry of Education, College of Biotechnology, Southwest University, Beibei, Chongqing 400715, China. xiaqy@swu.edu.cn

    We designed and constructed a genome-wide microarray with 22,987 70-mer oligonucleotides covering the presently known and predicted genes in the silkworm genome, and surveyed the gene expression in multiple silkworm tissues on day 3 of the fifth instar. Clusters of tissue-prevalent and tissue-specific genes and genes that are differentially expressed in different tissues were identified, and they reflect well major tissue-specific functions on the molecular level. The data presented in this study provide a new resource for annotating the silkworm genome.

    PMID: 17683582 [PubMed - indexed for MEDLINE]

    PMCID: 2374993

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