Format

Send to:

Choose Destination
See comment in PubMed Commons below
Fertil Steril. 2008 May;89(5):1069-72. Epub 2007 Aug 6.

Lymph node involvement and lymphovascular invasion in deep infiltrating rectosigmoid endometriosis.

Author information

  • 1Department of Pathology, Erasme University Hospital, Free University of Brussels, Brussels, Belgium. jenoel@ulb.ac.be

Abstract

OBJECTIVE:

To analyze the lymph node involvement by endometriotic foci in rectosigmoid endometriosis and to correlate it with clinical and histological parameters including the presence of lymphovascular invasions, which could explain this lymph node involvement.

DESIGN:

A prospective study of 26 consecutive cases of rectosigmoid endometriosis between January 2005 and January 2007.

SETTING:

A multidisciplinary study including clinical and pathological data.

PATIENT(S):

Twenty-six patients with symptomatic rectosigmoid endometriosis.

INTERVENTION(S):

Laparoscopic surgery with pathological analysis of each specimen.

MAIN OUTCOME MEASURE(S):

Involvement of lymph nodes by endometriotic foci was correlated with the size and the wall layers affected by endometriotic lesions, the number of lymph nodes retrieved, and the presence of lymphovascular invasions demonstrated by D2-40, a specific antibody to lymphatic vessels.

RESULT(S):

Lymph node involvement by endometriosis was observed in 11 of the 26 patients (42.3%) and correlated with the size of the lesions, the number of lymph nodes retrieved, and the presence of lymphovascular invasions, which were observed in 36.3% of cases.

CONCLUSION(S):

Our data confirm that lymph node involvement by endometriotic foci is a frequent event in rectosigmoid endometriosis and may result at least partially from a lymphatic spread of the disease.

PMID:
17681338
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk