Send to:

Choose Destination
See comment in PubMed Commons below
Genome Biol. 2007;8(8):R155.

RASTA-Bacteria: a web-based tool for identifying toxin-antitoxin loci in prokaryotes.

Author information

  • 1CNRS UMR6061 Génétique et Développement, Université de Rennes 1, IFR 140, Av, du Prof, Léon Bernard, CS 34317, 35043 Rennes, France.


Toxin/antitoxin (TA) systems, viewed as essential regulators of growth arrest and programmed cell death, are widespread among prokaryotes, but remain sparsely annotated. We present RASTA-Bacteria, an automated method allowing quick and reliable identification of TA loci in sequenced prokaryotic genomes, whether they are annotated open reading frames or not. The tool successfully confirmed all reported TA systems, and spotted new putative loci upon screening of sequenced genomes. RASTA-Bacteria is publicly available at

[PubMed - indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for BioMed Central Icon for PubMed Central
    Loading ...
    Write to the Help Desk