Proc Natl Acad Sci U S A. 1976 Mar;73(3):937-40.

Genetic variation in serum low density lipoproteins and lipid levels in man.

Berg K, Hames C, Dahlén G, Frick MH, Krishan I.

Abstract

Combined data from 10 different populations indicate that the serum cholesterol and triglyceride levels are higher in Ag(x-) than in Ag(x+) individuals. Although the differences were relatively small, they became more pronounced with increasing age. The Ag(x) antigen, which is associated with the serum low density lipoprotein, is genetically controlled and the present study therefore has revealed a small but significant effect of a single autosomal locus on lipids implicated in the pathogenesis of atherosclerosis. No explanation of the higher cholesterol and triglyceride levels in Ag(x-) than in Ag(x+) persons is apparent.

PMID:: 176662; [PubMed - indexed for MEDLINE]
PMCID:: PMC336035

Free PMC Article

Publication Types, MeSH Terms, Substances

Publication Types

MeSH Terms

Substances

LinkOut - more resources

Full Text Sources

Other Literature Sources

Labome Researcher Resource - ExactAntigen/Labome

Medical

Molecular Biology Databases

CHOLESTEROL - HSDB

Supplemental Content

Save items

Related citations in PubMed

Genetic lipoprotein variation and lipid levels in man. [Clin Genet. 1976]
Genetic lipoprotein variation and lipid levels in man.
Berg K, Hames C, Dahlén G, Frick MH, Krishan I. Clin Genet. 1976 Aug; 10(2NA-NA-760903-760909):97-103.
Associations of oral contraceptive use with serum lipids and lipoproteins in young women: the Bogalusa Heart Study. [Ann Epidemiol. 1997]
Associations of oral contraceptive use with serum lipids and lipoproteins in young women: the Bogalusa Heart Study.
Greenlund KJ, Webber LS, Srinivasan S, Wattigney W, Johnson C, Berenson GS. Ann Epidemiol. 1997 Nov; 7(8):561-7.
HDL cholesterol and other lipids in coronary heart disease. The cooperative lipoprotein phenotyping study. [Circulation. 1977]
HDL cholesterol and other lipids in coronary heart disease. The cooperative lipoprotein phenotyping study.
Castelli WP, Doyle JT, Gordon T, Hames CG, Hjortland MC, Hulley SB, Kagan A, Zukel WJ. Circulation. 1977 May; 55(5):767-72.
Nutrient intake: relationships with lipids and lipoproteins in 6--19-year-old children--the Princeton School District study. [Metabolism. 1980]
Nutrient intake: relationships with lipids and lipoproteins in 6--19-year-old children--the Princeton School District study.
Morrison JA, Larsen R, Glatfelter L, Boggs D, Burton K, Smith C, Kelly K, Mellies MJ, Khoury P, Glueck CJ. Metabolism. 1980 Feb; 29(2):133-40.
Hyperlipidemia in coronary heart disease. 3. Evaluation of lipoprotein phenotypes of 156 genetically defined survivors of myocardial infarction. [J Clin Invest. 1973]
Hyperlipidemia in coronary heart disease. 3. Evaluation of lipoprotein phenotypes of 156 genetically defined survivors of myocardial infarction.
Hazzard WR, Goldstein JL, Schrott MG, Motulsky AG, Bierman EL. J Clin Invest. 1973 Jul; 52(7):1569-77.

See reviews... See all...

Cited by 5 PubMed Central articles

Inheritance of low-density lipoprotein subclass patterns: results of complex segregation analysis. [Am J Hum Genet. 1988]
Inheritance of low-density lipoprotein subclass patterns: results of complex segregation analysis.
Austin MA, King MC, Vranizan KM, Newman B, Krauss RM. Am J Hum Genet. 1988 Dec; 43(6):838-46.
Genetic linkage between the antigenic group (Ag) variation and the apolipoprotein B gene: assignment of the Ag locus. [Proc Natl Acad Sci U S A. 1986]
Genetic linkage between the antigenic group (Ag) variation and the apolipoprotein B gene: assignment of the Ag locus.
Berg K, Powell LM, Wallis SC, Pease R, Knott TJ, Scott J. Proc Natl Acad Sci U S A. 1986 Oct; 83(19):7367-70.
Association between a specific apolipoprotein B mutation and familial defective apolipoprotein B-100. [Proc Natl Acad Sci U S A. 1989]
Association between a specific apolipoprotein B mutation and familial defective apolipoprotein B-100.
Soria LF, Ludwig EH, Clarke HR, Vega GL, Grundy SM, McCarthy BJ. Proc Natl Acad Sci U S A. 1989 Jan; 86(2):587-91.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound (MeSH Keyword)
PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Gene (OMIM)
Gene records associated with Online Mendelian Inheritance in Man (OMIM) records that cite the current articles in their reference lists.
Nucleotide (Weighted)
Nucleotide records associated with the current articles through the Gene database. These are the related sequences on the Gene record that are added manually by NCBI.
OMIM (calculated)
Online Mendelian Inheritance in Man (OMIM) records that include the current articles as references in the light bulb links within or in the citations at the end of the OMIM record. The references available through the light bulb link are collected using the PubMed related articles algorithm to identify records with similar terminology to the OMIM record.
OMIM (cited)
Online Mendelian Inheritance in Man (OMIM) records that include the current articles as reference cited at the end of the OMIM record.
Protein (Weighted)
Protein records associated with the current articles through related Gene database records. These are the related sequences on the Gene record that are added manually by NCBI.
References for this PMC Article
Citation referenced in PubMed article. Only valid for PubMed citations that are also in PMC.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Free in PMC
Free full text articles in PMC
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Genetic variation in serum low density lipoproteins and lipid levels in man.
Genetic variation in serum low density lipoproteins and lipid levels in man.
Proc Natl Acad Sci U S A. 1976 Mar ;73(3):937-40.

PubMed
Rationale for double renin-angiotensin-aldosterone system blockade.
Rationale for double renin-angiotensin-aldosterone system blockade.
Am J Cardiol. 2007 Aug 6 ;100(3A):25J-31J. Epub 2007 May 25 .

PubMed
Determination of glutamic acid decarboxylase antibodies (GADA) IgG subclasses - ...
Determination of glutamic acid decarboxylase antibodies (GADA) IgG subclasses - comparison of three immunoprecipitation assays (IPAs).
Clin Exp Immunol. 2007 Oct ;150(1):68-74. Epub 2007 Jul 30 .

PubMed
Moral hazard and consumer-driven health care: a fundamentally flawed concept.
Moral hazard and consumer-driven health care: a fundamentally flawed concept.
Int J Health Serv. 2007 ;37(2):333-51.

PubMed
[Substance use among night high school students in Japan].
[Substance use among night high school students in Japan].
Nihon Arukoru Yakubutsu Igakkai Zasshi. 2007 Jun ;42(3):152-64.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: