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Genome Biol. 2007;8(7):221.

A small RNA makes a Bic difference.

Author information

  • 1Cancer Immunology and AIDS, Dana-Farber Cancer Institute and Department of Pathology, Harvard Medical School, Boston, MA 02115, USA.

Abstract

The first highly specific knockouts of a microRNA, miR155, in mice result in multiple defects in adaptive immunity, and also show the feasibility of investigating at least some microRNAs by gene knockout.

PMID:
17666120
[PubMed - indexed for MEDLINE]
PMCID:
PMC2323214
Free PMC Article
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