Surgical treatment of epilepsy with chronic cerebral granuloma caused by Schistosoma japonicum

Epilepsia. 2008 Jan;49(1):73-9. doi: 10.1111/j.1528-1167.2007.01219.x. Epub 2007 Jul 28.

Abstract

Purpose: To study the surgical treatment of epilepsy with cerebral granuloma caused by Schistosoma japonicum.

Methods: Two hundred fifty cases of epilepsy caused by cerebral schistosomiasis from 1955 to 2004 were analyzed retrospectively.

Results: There were no deaths. Follow-up of 196 cases for 4-5 years after operation demonstrated that 180 cases (92%) were seizure-free or well-controlled.

Conclusions: Surgical treatment should be considered when drug therapy fails to control epilepsy or the lesion shows mass effect. Intraoperative electrocorticography monitoring is helpful to define the extent of the resection of the lesion.

Publication types

  • Comparative Study

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Animals
  • Brain Diseases / diagnosis
  • Brain Diseases / parasitology
  • Brain Diseases / surgery*
  • Brain Mapping
  • Central Nervous System Helminthiasis / parasitology
  • Central Nervous System Helminthiasis / pathology
  • Central Nervous System Helminthiasis / surgery*
  • China / epidemiology
  • Chronic Disease
  • Electroencephalography / statistics & numerical data
  • Epilepsy / diagnosis
  • Epilepsy / parasitology*
  • Epilepsy / pathology
  • Epilepsy / surgery*
  • Female
  • Follow-Up Studies
  • Granuloma / parasitology
  • Granuloma / pathology
  • Granuloma / surgery*
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Monitoring, Intraoperative
  • Parietal Lobe / pathology
  • Preoperative Care
  • Retrospective Studies
  • Schistosoma japonicum / isolation & purification
  • Schistosomiasis japonica / epidemiology
  • Schistosomiasis japonica / pathology
  • Schistosomiasis japonica / surgery*
  • Survival Analysis