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    Ir J Med Sci. 2008 Mar;177(1):63-6. Epub 2007 Jul 28.

    Elevated CA 125 and ascites: not always malignancy.

    Source

    Department of Cardiovascular Therapeutics and Pharmacology, Whitla Medical Building, Queen's University Belfast, 97 Lisburn Road, Belfast, BT9 7BL, Northern Ireland. clockhart01@qub.ac.uk

    Abstract

    BACKGROUND:

    We present two clinical cases from a single institution where a final diagnosis of cardiac failure was made following the initial finding of ascites and an elevated CA 125 level. In both cases gynaecological malignancy was initially suspected.

    METHODS:

    Following negative confirmatory tests for gynaecological malignancy, echocardiography was undertaken.

    RESULTS:

    Patient 1 had severe right ventricular dilatation and dysfunction. Patient 2 had biventricular dysfunction with pulmonary hypertension. Both patients responded to standard therapy for heart failure, including loop diuretics.

    PMID:
    17661125
    [PubMed - indexed for MEDLINE]

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