Successful treatment of ctx-m ESBL producing Escherichia coli relapsing pyelonephritis with long term pivmecillinam

Lindsay E Nicolle; Michael R Mulvey

doi:10.1080/00365540701367801

Successful treatment of ctx-m ESBL producing Escherichia coli relapsing pyelonephritis with long term pivmecillinam

Scand J Infect Dis. 2007;39(8):748-9. doi: 10.1080/00365540701367801.

Authors

Lindsay E Nicolle¹, Michael R Mulvey

Affiliation

¹ Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, Canada. lnicolle@hsc.mb.ca

PMID: 17654359
DOI: 10.1080/00365540701367801

Abstract

Oral therapy options for pyelonephritis caused by ESBL producing E. coli are limited. We describe a woman with relapsing pyelonephritis due to a CTX-M ESBL E. coli who was cured with a prolonged course of pivmecillinam. This suggests pivmecillinam may be effective treatment for selected patients with pyelonephritis with these organisms.

Publication types

Case Reports

MeSH terms

Adult
Amdinocillin Pivoxil / therapeutic use*
Anti-Bacterial Agents / therapeutic use*
Drug Resistance, Multiple, Bacterial / drug effects
Escherichia coli / drug effects
Escherichia coli / enzymology*
Escherichia coli Infections / drug therapy*
Female
Humans
Pyelonephritis / drug therapy*
Pyelonephritis / microbiology
beta-Lactamases / genetics
beta-Lactamases / metabolism

Substances

Anti-Bacterial Agents
Amdinocillin Pivoxil
beta-lactamase CTX-M-15
beta-Lactamases