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    Gastroenterol Clin Biol. 2007 Jun-Jul;31(6-7):607-10.

    [Crohn's disease and the SAPHO syndrome during treatment with infliximab: a case report and review of literature]

    [Article in French]

    Van Den Eynde M, Lecluyse K, Chioccioli C, Brouckaert M, Caussin E, Lammens P.

    Service de Gastroentérologie, Clinique Saint-Jean, boulevard du Jardin Botanique 32, 1000 Brussels.

    We report the case of a 40 year-old Turkish woman with severe ileal Crohn's disease associated with palmoplantar pustulosis and aseptic spondylitis, also known as the SAPHO syndrome. However, in the present case, the syndrome developed three months after starting infliximab (Remicade) therapy, which is generally used to treat the SAPHO syndrome. This case-report discusses the unclear relationship between Crohn's disease, the appearance of a SAPHO syndrome and treatment with infliximab.

    PMID: 17646788 [PubMed - indexed for MEDLINE]

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