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Nat Chem Biol. 2007 Aug;3(8):438-41.

Reporting data from high-throughput screening of small-molecule libraries.

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  • 1US National Institutes of Health Chemical Genomics Center, National Human Genome Institute, National Institutes of Health, 9800 Medical Center Drive, Bethesda, Maryland 20892-3370, USA.


Publications reporting results of small-molecule screens are becoming more common as academic researchers increasingly make use of high-throughput screening (HTS) facilities. However, no standards have been formally established for reporting small-molecule screening data, and often key information important for the evaluation and interpretation of results is omitted in published HTS protocols. Here, we propose concise guidelines for reporting small-molecule HTS data.

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